Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1196328 | 0.84 | GAA (0.78) | SMN1; SMN2GAAKMT2AHSD17B10LMNA | |
| SCHEMBL26212484 | 0.83 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL12443609 | 0.83 | NPC1 (0.62) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL26733447 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL7214340 | 0.83 | L3MBTL1 (0.69) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL12443610 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL26716442 | 0.82 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL12760632 | 0.82 | L3MBTL1 (0.72) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL18193849 | 0.82 | GAA (0.57) | SMN1; SMN2NPC1RAB9AGAAKMT2A | |
| SCHEMBL31055397 | 0.82 | L3MBTL1 (0.72) | SMN1; SMN2NPC1RAB9AGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981854-B1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-06-01 | — | — | EP | claimed |