Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12760632 | 1.00 | L3MBTL1 (0.72) | L3MBTL1NPC1RAB9ATP53BP1LMNA | |
| SCHEMBL31055430 | 0.84 | KMT2A (0.78) | L3MBTL1NPC1RAB9ATP53BP1LMNA | |
| SCHEMBL1928397 | 0.84 | L3MBTL1 (1.00) | L3MBTL1NPC1RAB9ATP53BP1LMNA | |
| SCHEMBL15676734 | 0.84 | SMN1; SMN2 (0.55) | L3MBTL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL26212484 | 0.83 | SMN1; SMN2 (0.57) | L3MBTL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL26733447 | 0.83 | SMN1; SMN2 (0.61) | L3MBTL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL12443609 | 0.83 | NPC1 (0.62) | NPC1RAB9ALMNASMN1; SMN2KMT2A | |
| SCHEMBL1921045 | 0.82 | SMN1; SMN2 (0.56) | L3MBTL1NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL18193849 | 0.82 | GAA (0.57) | NPC1RAB9ALMNASMN1; SMN2KMT2A | |
| SCHEMBL12443610 | 0.82 | SMN1; SMN2 (0.62) | NPC1RAB9ALMNASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118480001-A | C-Kit (V559D)/PDGFR beta double-target allosteric inhibitor and preparation method, pharmaceutical composition and application thereof | 贵州省天然产物研究中心 | 2024-08-13 | — | — | CN | disclosed |