Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19210502 | 0.91 | PPARD (0.43) | PPARDL3MBTL1RAB9ANPC1TDP1 | |
| SCHEMBL2704589 | 0.89 | PPARD (0.52) | PPARDL3MBTL1RAB9ANPC1TDP1 | |
| SCHEMBL19210500 | 0.87 | L3MBTL1 (0.43) | PPARDL3MBTL1RAB9ANPC1TDP1 | |
| SCHEMBL201521 | 0.86 | PPARD (0.49) | PPARDL3MBTL1RAB9ANPC1TDP1 | |
| SCHEMBL204423 | 0.86 | L3MBTL1 (0.45) | PPARDL3MBTL1RAB9ANPC1TDP1 | |
| SCHEMBL2705816 | 0.86 | L3MBTL1 (0.53) | PPARDL3MBTL1RAB9ANPC1TDP1 | |
| SCHEMBL2707296 | 0.84 | RAB9A (0.54) | PPARDL3MBTL1RAB9ANPC1TDP1 | |
| SCHEMBL17275085 | 0.84 | EPHA2 (0.46) | PPARDL3MBTL1RAB9ANPC1TDP1 | |
| SCHEMBL201734 | 0.83 | PPARD (0.51) | PPARDL3MBTL1RAB9ANPC1TDP1 | |
| SCHEMBL17275068 | 0.83 | NPC1 (0.38) | PPARDL3MBTL1RAB9ANPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699557-B1 | 3-(OXAZOL-2-YL-ETHOXY)- AND 3-(THIAZOL-2-YL-ETHOXY)-BENZAMIDE DERIVATIVES AS ANTI-BACTERIAL AGENTS | BIOTA SCIENT MANAGEMENT (AU) | 2017-08-16 | — | — | EP | disclosed |