Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19211506 | 0.87 | — | — | |
| SCHEMBL19211438 | 0.85 | CNR2 (0.33) | — | |
| SCHEMBL19211408 | 0.80 | CNR2 (0.33) | — | |
| SCHEMBL19211490 | 0.80 | — | — | |
| SCHEMBL19211376 | 0.79 | RXRA (0.31) | RXRAGRIN1GRIN2B | |
| SCHEMBL19211394 | 0.76 | CNR2 (0.36) | RXRAGRIN1GRIN2B | |
| SCHEMBL19211505 | 0.66 | PDCD1 (0.33) | — | |
| SCHEMBL19211437 | 0.64 | CNR2 (0.35) | — | |
| SCHEMBL19211407 | 0.59 | CNR2 (0.35) | — | |
| SCHEMBL19211590 | 0.59 | JAK2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414233-A1 | SUBSTITUTED 1,2,3-TRIAZOLES AS NR2B-SELECTIVE NMDA MODULATORS | Janssen Pharmaceutica NV (BE) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017139428-A1 | SUBSTITUTED 1,2,3-TRIAZOLES AS NR2B-SELECTIVE NMDA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-17 | — | — | WO | disclosed |