Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19211376 | 0.92 | RXRA (0.31) | — | |
| SCHEMBL19211394 | 0.91 | CNR2 (0.36) | CNR2 | |
| SCHEMBL19211506 | 0.83 | — | — | |
| SCHEMBL19211438 | 0.81 | CNR2 (0.33) | CNR2 | |
| SCHEMBL19211491 | 0.80 | RXRA (0.30) | — | |
| SCHEMBL19211407 | 0.78 | CNR2 (0.35) | CNR2 | |
| SCHEMBL19211375 | 0.70 | — | — | |
| SCHEMBL19211392 | 0.70 | CNR2 (0.35) | CNR2 | |
| SCHEMBL29829084 | 0.64 | HSD11B1 (0.35) | — | |
| SCHEMBL19211505 | 0.61 | PDCD1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414233-A1 | SUBSTITUTED 1,2,3-TRIAZOLES AS NR2B-SELECTIVE NMDA MODULATORS | Janssen Pharmaceutica NV (BE) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017139428-A1 | SUBSTITUTED 1,2,3-TRIAZOLES AS NR2B-SELECTIVE NMDA MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-08-17 | — | — | WO | disclosed |