Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2964830 | 0.88 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2ATDP1GAAKDM4E | |
| SCHEMBL7325840 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2KMT2ATDP1GAAKDM4E | |
| SCHEMBL7329867 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2KMT2ATDP1GAAKDM4E | |
| SCHEMBL19211610 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2KMT2ATDP1KDM4EALDH1A1 | |
| SCHEMBL7332282 | 0.81 | TDP1 (0.39) | SMN1; SMN2KMT2ATDP1GAAKDM4E | |
| SCHEMBL8684974 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2ATDP1GAAKDM4E | |
| SCHEMBL20558636 | 0.80 | ABL1 (0.41) | SMN1; SMN2KMT2AGAAALDH1A1LMNA | |
| SCHEMBL20558611 | 0.80 | CA12 (0.40) | SMN1; SMN2KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL13215874 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2ATDP1KDM4EALDH1A1 | |
| SCHEMBL9868368 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2ATDP1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103804211-B | The synthetic method of 4-(acetylamino)-2-hydroxyl-3-(2-carbonylethyl) methyl benzoate | TIANJIN WEIJIE TECHNOLOGY CO., LTD. (CN) | 2016-04-06 | — | — | CN | claimed |
| CN-103804211-A | Synthetic method of 4-(acetyl amino)-2-hydroxy-3-(2-carbonyl ethyl) methyl benzoate | TIANJIN WEIJIE TECHNOLOGY CO LTD | 2014-05-21 | — | — | CN | claimed |
| EP-3413891-B1 | PROCESSES FOR THE PREPARATION OF HIGHLY PURE PRUCALOPRIDE SUCCINATE | SYMED LABS LTD (IN) | 2024-01-03 | — | — | EP | disclosed |
| EP-3413891-A1 | PROCESSES FOR THE PREPARATION OF HIGHLY PURE PRUCALOPRIDE SUCCINATE AND ITS INTERMEDIATES | Symed Labs Limited (IN) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017137910-A1 | PROCESSES FOR THE PREPARATION OF HIGHLY PURE PRUCALOPRIDE SUCCINATE AND ITS INTERMEDIATES | SYMED LABS LIMITED (IN) | 2017-08-17 | — | — | WO | disclosed |
| WO-2017137910-A1 | PROCESSES FOR THE PREPARATION OF HIGHLY PURE PRUCALOPRIDE SUCCINATE AND ITS INTERMEDIATES | SYMED LABS LIMITED (IN) | 2017-08-17 | — | — | WO | disclosed |
| CN-103804211-B | The synthetic method of 4-(acetylamino)-2-hydroxyl-3-(2-carbonylethyl) methyl benzoate | TIANJIN WEIJIE TECHNOLOGY CO., LTD. (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-103804211-B | The synthetic method of 4-(acetylamino)-2-hydroxyl-3-(2-carbonylethyl) methyl benzoate | TIANJIN WEIJIE TECHNOLOGY CO., LTD. (CN) | 2016-04-06 | — | — | CN | disclosed |
| CN-103804211-A | Synthetic method of 4-(acetyl amino)-2-hydroxy-3-(2-carbonyl ethyl) methyl benzoate | TIANJIN WEIJIE TECHNOLOGY CO LTD | 2014-05-21 | — | — | CN | disclosed |
| CN-103804211-A | Synthetic method of 4-(acetyl amino)-2-hydroxy-3-(2-carbonyl ethyl) methyl benzoate | TIANJIN WEIJIE TECHNOLOGY CO LTD | 2014-05-21 | — | — | CN | disclosed |
| CN-103804211-A | Synthetic method of 4-(acetyl amino)-2-hydroxy-3-(2-carbonyl ethyl) methyl benzoate | TIANJIN WEIJIE TECHNOLOGY CO LTD | 2014-05-21 | — | — | CN | disclosed |