Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960041 | 0.89 | CYP11B1 (0.46) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL5222724 | 0.87 | CYP11B1 (0.47) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL16673120 | 0.84 | CYP3A4 (0.62) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL12767805 | 0.82 | CYP3A4 (0.41) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL27670476 | 0.82 | CYP11B1 (0.43) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL5228601 | 0.82 | CYP3A4 (0.41) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL12838345 | 0.82 | ENPP2 (0.42) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL27572539 | 0.82 | IDO1 (0.41) | CYP3A4LMNAMAPTENPP2MKNK1 | |
| SCHEMBL5223331 | 0.81 | ADH5 (0.55) | CYP3A4MAPTENPP2MKNK1MKNK2 | |
| SCHEMBL870900 | 0.80 | IDO1 (0.64) | CYP3A4LMNAMAPTENPP2MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3414216-B1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2020-10-21 | — | — | EP | claimed |
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2019-02-07 | — | — | US | claimed |
| EP-3414216-A1 | ARYLATION OF ALIPHATIC AMINES | AAA Chemistry ApS (DK) | 2018-12-19 | — | — | EP | claimed |
| WO-2017137047-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2017-08-17 | — | — | WO | claimed |
| WO-2023134713-A1 | FUSED AZAHETEROCYCLIC DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 南方科技大学 | 2023-07-20 | — | — | WO | disclosed |
| CN-115974872-A | Aza-and-ring derivatives, pharmaceutical compositions thereof and uses thereof | 南方科技大学 | 2023-04-18 | — | — | CN | disclosed |
| EP-3414216-B1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2020-10-21 | — | — | EP | disclosed |
| EP-3414216-B1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2020-10-21 | — | — | EP | disclosed |
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2019-02-07 | — | — | US | disclosed |
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2019-02-07 | — | — | US | disclosed |
| CN-109071374-A | The arylation of fatty amine | AAA化学公司 | 2018-12-21 | — | — | CN | disclosed |
| EP-3414216-A1 | ARYLATION OF ALIPHATIC AMINES | AAA Chemistry ApS (DK) | 2018-12-19 | — | — | EP | disclosed |
| WO-2017137047-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2017-08-17 | — | — | WO | disclosed |
| WO-2017137047-A1 | ARYLATION OF ALIPHATIC AMINES | AAA CHEMISTRY APS (DK) | 2017-08-17 | — | — | WO | disclosed |
| CN-102014900-B | Method of treating cancer using a neuropeptide Y5R (NPY5R) antagonist | UNIV HEALTH NETWORK | 2014-04-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190040028-A1 | ARYLATION OF ALIPHATIC AMINES | NAT1, AHR, ABL1 | CYP3A4 242/4885LMNA 2612/4885MAPT 2503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.