Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18660230 | 0.97 | ALDH1A1 (0.47) | ALDH1A1PAOXACHECES2LMNA | |
| SCHEMBL14445051 | 0.95 | PAOX (0.48) | ALDH1A1PAOXACHECES2LMNA | |
| SCHEMBL8016543 | 0.90 | CES2 (0.48) | ALDH1A1PAOXACHECES2TSHR | |
| SCHEMBL3422249 | 0.90 | TSHR (0.52) | ALDH1A1PAOXACHECES2LMNA | |
| SCHEMBL18996625 | 0.90 | CES2 (0.54) | ALDH1A1CES2TSHR | |
| SCHEMBL148224 | 0.89 | PAOX (0.54) | ALDH1A1PAOXACHECES2LMNA | |
| SCHEMBL15223707 | 0.88 | TSHR (0.50) | ALDH1A1PAOXACHECES2LMNA | |
| SCHEMBL20932438 | 0.88 | CES2 (0.63) | ALDH1A1CES2TSHR | |
| SCHEMBL15218245 | 0.88 | CES2 (0.57) | ALDH1A1PAOXACHECES2LMNA | |
| SCHEMBL28886788 | 0.88 | TSHR (0.50) | ALDH1A1PAOXACHECES2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805822-A | Polymer molecular brush with multi-block side chain and preparation method and application thereof | 南京大学 | 2022-07-29 | — | — | CN | disclosed |
| CN-114206883-A | Oxopyridine fused ring derivative and pharmaceutical composition comprising the same | 伟迈可生物有限公司 | 2022-03-18 | — | — | CN | disclosed |
| CN-114129468-A | Polysaccharide composition with functions of improving skin immunity and strengthening skin barrier function and application thereof | 无限极（中国）有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-114052259-A | Composition with skin aging delaying effect and application thereof | 广东海洋大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-112426425-B | Use of citrusinine-II for the preparation of agents affecting the perception of itch and pain in humans and animals | 中国科学院昆明动物研究所 | 2021-10-29 | — | — | CN | disclosed |
| CN-111825624-B | Ester-water amphiphilic hypocrellin derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2021-07-27 | — | — | CN | disclosed |
| CN-107935943-B | Ester-water amphiphilic hypocrellin derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2021-06-29 | — | — | CN | disclosed |
| CN-112426425-A | Use of citrusinine-II for the preparation of agents affecting the perception of itch and pain in humans and animals | 中国科学院昆明动物研究所 | 2021-03-02 | — | — | CN | disclosed |
| CN-111825624-A | Ester-water amphiphilic hypocrellin derivative and preparation method and application thereof | 中国科学院理化技术研究所 | 2020-10-27 | — | — | CN | disclosed |
| WO-2017205309-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-11-30 | — | — | WO | disclosed |
| US-4542018-A | ANTIBIOTICS | GRUPPO LEPETIT S.P.A. (IT) | 1985-09-17 | — | — | US | disclosed |
| US-4514416-A | Amidine compound, process for producing same and anti-complement agent comprising same | TORII & CO. LTD. (JP) | 1985-04-30 | — | — | US | disclosed |
| US-4349666-A | Process for the production of kanomycin B derivatives and products obtained therefrom | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1982-09-14 | — | — | US | disclosed |
| US-4235775-A | Triazolobenzodiazepine derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1980-11-25 | — | — | US | disclosed |
| US-4153688-A | N-TRIFLUOROACETYL-ALANYL OR LYSYL-ALANYL OR LYSYL-ANILIDE, REVERSIBLE ELASTASE ENZYME INHIBITORS | DELALANDE S.A. (FR) | 1979-05-08 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4124710-A | HYPOTENSIVE AGENTS | LABAZ (FR) | 1978-11-07 | — | — | US | disclosed |
| US-4038459-A | BATTERY;WATER INSOLUBLE COMPLEX | ECO-CONTROL, INC. (US) | 1977-07-26 | — | — | US | disclosed |
| US-4035567-A | Process for producing the methyl ester of amphotericin B | E. R. SQUIBB & SONS, INC. (US) | 1977-07-12 | — | — | US | disclosed |
| US-3957828-A | 3-Aminoalkyl-1,3-dihydro-3-phenylspiro[isobenzofurans] | AMERICAN HOECHST CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |