Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 17/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.39 |
| ▸ | KLK1 | P06870 | 2/20 | 0.39 |
| ▸ | PLAT | P00750 | 2/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.38 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | F12 | P00748 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 2/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1197594 | 0.86 | F11 (0.46) | F11KLKB1KLK1PLATPRSS1 | |
| SCHEMBL1197597 | 0.86 | F11 (0.46) | F11KLKB1KLK1PLATPRSS1 | |
| SCHEMBL1197600 | 0.86 | F11 (0.46) | F11KLKB1KLK1PLATPRSS1 | |
| SCHEMBL1197603 | 0.86 | F11 (0.46) | F11KLKB1KLK1PLATPRSS1 | |
| SCHEMBL1920914 | 0.83 | F11 (0.40) | F11KLKB1KLK1PLATPRSS1 | |
| SCHEMBL1920746 | 0.79 | F11 (0.66) | F11KLKB1KLK1PLATF10 | |
| SCHEMBL12012926 | 0.79 | F11 (0.39) | F11KLKB1KLK1PLATPRSS1 | |
| SCHEMBL1196460 | 0.69 | F11 (0.51) | F11KLKB1KLK1PLATPRSS1 | |
| SCHEMBL1196466 | 0.69 | F11 (0.51) | F11KLKB1KLK1PLATPRSS1 | |
| SCHEMBL1197206 | 0.69 | F11 (0.47) | F11KLKB1KLK1PLATPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981854-B1 | ARYLPROPIONAMIDE, ARYLACRYLAMIDE, ARYLPROPYNAMIDE, OR ARYLMETHYLUREA ANALOGS AS FACTOR XIA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2011-06-01 | — | — | EP | claimed |