SCHEMBL1921379

SCHEMBL1921379

O=P(O)(F)OC(c1ccccc1F)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36
ACP3 P15309 1/20 0.36
POLB P06746 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PTPN1 P18031 1/20 0.34
GAA P10253 2/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HPGD P15428 1/20 0.33
IDO1 P14902 1/20 0.33
TDO2 P48775 1/20 0.33
PGK1 P00558 2/20 0.33
PGK2 P07205 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276917 0.88 CES2 (0.39) CYP3A4CES2CES1ACP3POLB
SCHEMBL1276957 0.78 POLB (0.51) ACP3POLBPTPN1GAANPSR1
SCHEMBL18526933 0.70 PGK1 (0.50) CYP3A4CES2CES1ACP3MEN1
SCHEMBL18094428 0.69 IDO1 (0.37) CYP3A4CES2CES1MEN1KMT2A
SCHEMBL778849 0.67 ACP3 (0.47) CYP3A4CES2CES1ACP3MEN1
SCHEMBL778114 0.67 ACP3 (0.41) CYP3A4CES2CES1ACP3POLB
SCHEMBL781643 0.67 CYP3A4 (0.38) CYP3A4CES2CES1ACP3MEN1
SCHEMBL23489959 0.65 CES2 (0.46) CYP3A4CES2CES1MEN1KMT2A
SCHEMBL14322064 0.65 CES2 (0.46) CYP3A4CES2CES1MEN1KMT2A
SCHEMBL28288495 0.65 CES2 (0.46) CES2CES1MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2330675-B1 SECONDARY BATTERY NEC CORP (JP) 2018-08-22 EP disclosed
EP-2330675-A1 SECONDARY BATTERY NEC Corporation (JP) 2011-06-08 EP disclosed