Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14996377 | 0.91 | ESR1 (0.62) | ALDH1A1PRKCATDP1TSHRADRB2 | |
| SCHEMBL15382001 | 0.89 | NPC1 (0.54) | ALDH1A1PRKCAADRB2ADRB1ADRB3 | |
| SCHEMBL9487484 | 0.88 | ALDH1A1 (0.52) | ALDH1A1PRKCATDP1ADRB2ADRB1 | |
| SCHEMBL6937392 | 0.88 | TSHR (0.54) | ALDH1A1PRKCATSHRADRB2ADRB1 | |
| SCHEMBL9488693 | 0.85 | GAA (0.50) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL8549773 | 0.85 | ESR1 (0.50) | ALDH1A1TDP1TSHRTP53SLC6A3 | |
| SCHEMBL8549771 | 0.85 | ALDH1A1 (0.59) | ALDH1A1PRKCATDP1TSHRADRB2 | |
| SCHEMBL9490214 | 0.84 | ALDH1A1 (0.44) | ALDH1A1PRKCAADRB2ADRB1ADRB3 | |
| SCHEMBL9488474 | 0.84 | ALDH1A1 (0.44) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL9488091 | 0.84 | MAPT (0.49) | ALDH1A1PRKCATSHRADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221257-B2 | Polymer with releasable gas | ROHM AND HAAS COMPANY (US) | 2019-03-05 | — | — | US | disclosed |
| US-20170226239-A1 | POLYMER WITH RELEASABLE GAS | ROHM AND HAAS COMPANY (US) | 2017-08-10 | — | — | US | disclosed |
| US-20170226239-A1 | POLYMER WITH RELEASABLE GAS | ROHM AND HAAS COMPANY (US) | 2017-08-10 | — | — | US | disclosed |