Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19214520 | 0.85 | ALDH1A1 (0.61) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL13168067 | 0.83 | ALDH1A1 (0.47) | ALDH1A1TSHRKMT2A | |
| SCHEMBL784821 | 0.81 | ALDH1A1 (0.65) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL21386572 | 0.81 | ALDH1A1 (0.41) | ALDH1A1ADRB2ADRB1ADRB3SLC1A5 | |
| SCHEMBL6937392 | 0.80 | TSHR (0.54) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL23817190 | 0.80 | KMT2A (0.44) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL22474313 | 0.80 | KMT2A (0.44) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL11185985 | 0.79 | ALDH1A1 (0.68) | ALDH1A1ADRB2ADRB1ADRB3LMNA | |
| SCHEMBL91606 | 0.79 | L3MBTL1 (0.59) | ALDH1A1LMNATDP1TSHRKMT2A | |
| SCHEMBL17429724 | 0.79 | ALDH1A1 (0.62) | ALDH1A1ADRB2ADRB1ADRB3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737187-B1 | BENZOXAZINE DERIVATIVES, METHODS FOR OBTAINING SAME AND THEIR USE AS DRUGS | PHARMASCIENCE LAB (FR) | 1999-05-06 | — | — | EP | disclosed |
| EP-0737187-A1 | BENZOXAZINE DERIVATIVES, METHODS FOR OBTAINING SAME AND THEIR USE AS DRUGS | Laboratoires Pharmascience (FR) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018114-A1 | BENZOXAZINE DERIVATIVES, METHODS FOR OBTAINING SAME AND THEIR USE AS DRUGS | LABORATOIRES PHARMASCIENCE (FR) | 1995-07-06 | — | — | WO | disclosed |