SCHEMBL1921482

SCHEMBL1921482

FC(F)(F)c1cccc(Nc2ccc(Nc3cccc(C(F)(F)F)c3)cc2)c1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 8/20 0.70
▸ IDH2 P48735 2/20 0.68
▸ MAPT P10636 3/20 0.61
▸ SMN1; SMN2 Q16637 2/20 0.61
▸ ALDH1A1 P00352 2/20 0.61
▸ GAA P10253 2/20 0.61
▸ RAPGEF4 Q8WZA2 1/20 0.61
▸ RAB9A P51151 1/20 0.61
▸ APP P05067 2/20 0.58
▸ AKR1C3 P42330 1/20 0.56
▸ AKR1C2 P52895 1/20 0.56
▸ TP53 P04637 1/20 0.55
▸ NPSR1 Q6W5P4 1/20 0.55
▸ TDP1 Q9NUW8 1/20 0.55
▸ AURKA O14965 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394991 0.96 KIF11 (0.70) KIF11IDH2MAPTSMN1; SMN2ALDH1A1
SCHEMBL1921505 0.94 KIF11 (0.64) KIF11IDH2MAPTSMN1; SMN2ALDH1A1
SCHEMBL7347670 0.94 IDH2 (0.77) KIF11IDH2MAPTSMN1; SMN2ALDH1A1
SCHEMBL30575363 0.94 IDH2 (0.77) KIF11IDH2MAPTSMN1; SMN2ALDH1A1
SCHEMBL28141909 0.91 KIF11 (0.60) KIF11IDH2MAPTSMN1; SMN2ALDH1A1
SCHEMBL8971887 0.91 APP (0.69) KIF11IDH2MAPTSMN1; SMN2ALDH1A1
SCHEMBL16411339 0.91 KIF11 (0.65) KIF11IDH2MAPTSMN1; SMN2ALDH1A1
SCHEMBL10568041 0.87 KIF11 (0.71) KIF11IDH2MAPTSMN1; SMN2ALDH1A1
SCHEMBL5543915 0.87 IDH2 (0.58) KIF11IDH2MAPTSMN1; SMN2ALDH1A1
SCHEMBL9224466 0.86 KIF11 (0.60) KIF11IDH2MAPTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109369914-B High polymer material composition and preparation method and application thereof 江阴骏驰新材料科技有限公司 2020-08-07 — — CN disclosed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 — — EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 — — EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 — — US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 — — US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 — — US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 — — EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 — — US disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 — — US disclosed
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