Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.69 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | KIF11 | P52732 | 5/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.59 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.59 |
| ▸ | CDK2 | P24941 | 1/20 | 0.59 |
| ▸ | CDK7 | P50613 | 1/20 | 0.59 |
| ▸ | CCNH | P51946 | 1/20 | 0.59 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.59 |
| ▸ | IDH2 | P48735 | 3/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1921482 | 0.91 | KIF11 (0.70) | APPRAPGEF4MAPTGAATDP1 | |
| SCHEMBL9070348 | 0.87 | RAPGEF4 (0.68) | APPRAPGEF4MAPTGAATDP1 | |
| SCHEMBL394991 | 0.87 | KIF11 (0.70) | RAPGEF4MAPTGAATDP1KIF11 | |
| SCHEMBL1921505 | 0.85 | KIF11 (0.64) | APPRAPGEF4MAPTGAATDP1 | |
| SCHEMBL30575363 | 0.85 | IDH2 (0.77) | RAPGEF4MAPTGAAKIF11IDH2 | |
| SCHEMBL7347670 | 0.85 | IDH2 (0.77) | RAPGEF4MAPTGAAKIF11IDH2 | |
| SCHEMBL16411339 | 0.82 | KIF11 (0.65) | APPRAPGEF4MAPTGAATDP1 | |
| SCHEMBL28141909 | 0.82 | KIF11 (0.60) | APPRAPGEF4MAPTGAAKIF11 | |
| SCHEMBL4937177 | 0.81 | KIF11 (0.56) | APPRAPGEF4MAPTGAAKIF11 | |
| SCHEMBL9069757 | 0.81 | APP (0.71) | APPRAPGEF4MAPTGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0475676-B1 | Electrophotographic member | HITACHI CHEMICAL CO LTD (JP) | 1996-04-03 | — | — | EP | disclosed |
| EP-0620122-B1 | Thermosensitive recording material | NEW OJI PAPER CO LTD (JP) | 1996-03-13 | — | — | EP | disclosed |
| EP-0620122-A1 | Thermosensitive recording material | NEW OJI PAPER CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |