SCHEMBL19214860

SCHEMBL19214860

CCC(Cc1ccccn1)NCc1cccc(NCc2ccccc2)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP1 P07148 1/20 0.49
FABP6 P51161 1/20 0.49
APP P05067 4/20 0.45
CXCR4 P61073 1/20 0.43
KDM4E B2RXH2 3/20 0.41
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
TP53 P04637 2/20 0.40
TSHR P16473 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ACHE P22303 1/20 0.39
ESR1 P03372 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
NOS2 P35228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20661516 0.86 FABP1 (0.51) FABP1FABP6APPCXCR4KDM4E
SCHEMBL18157950 0.81 FABP1 (0.49) FABP1FABP6APPCXCR4KDM4E
SCHEMBL19214814 0.80 HRH3 (0.39) APPKDM4ETSHRSMN1; SMN2CYP1A2
SCHEMBL19214785 0.79 TRPV3 (0.40) KDM4ETSHRSMN1; SMN2CYP1A2CYP2D6
SCHEMBL20024577 0.79 FABP1 (0.61) FABP1FABP6APPCXCR4KDM4E
SCHEMBL19214859 0.78 POLB (0.39) APPKDM4ERAB9ATSHRSMN1; SMN2
SCHEMBL19214809 0.78 PTPRA (0.44) KDM4ENPC1RAB9ATSHRSMN1; SMN2
SCHEMBL20661470 0.73 HRH3 (0.33) APPCXCR4KDM4ERAB9ATSHR
SCHEMBL20032083 0.72 KDM4E (0.35) APPKDM4ETSHRSMN1; SMN2CYP1A2
SCHEMBL18114415 0.72 SMN1; SMN2 (0.47) FABP1FABP6KDM4ETSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 FABP1 2465/4885FABP6 2365/4885APP 73/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.