Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10165226 | 0.88 | HSD11B1 (0.59) | HSD11B1NR1H3 | |
| SCHEMBL15459955 | 0.81 | HSD11B1 (0.53) | HSD11B1NR1H3 | |
| SCHEMBL25753451 | 0.81 | HSD11B1 (0.53) | HSD11B1NR1H3 | |
| SCHEMBL2102455 | 0.79 | HSD11B1 (0.72) | HSD11B1NR1H3 | |
| SCHEMBL11920703 | 0.79 | MLYCD (0.52) | HSD11B1NR1H3 | |
| SCHEMBL5530921 | 0.79 | MLYCD (0.52) | HSD11B1NR1H3 | |
| SCHEMBL14697375 | 0.79 | HSD11B1 (0.72) | HSD11B1NR1H3 | |
| SCHEMBL8482502 | 0.79 | ESR1 (0.56) | HSD11B1 | |
| SCHEMBL18846 | 0.77 | HSD11B1 (0.54) | HSD11B1NR1H3 | |
| SCHEMBL19219 | 0.77 | HSD11B1 (0.54) | HSD11B1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027261-A1 | SULFONYLPIPERAZINE DERIVATIVES THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN FOR THE TREATMENT OF DIABETES | AMGEN INC. (US) | 2012-03-01 | — | — | WO | disclosed |