SCHEMBL19215822

SCHEMBL19215822

FC1=CCCC=C1C1CCCC1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23139115 0.70 MAOA (0.33) MAOAMAOBMAPT
SCHEMBL21526240 0.68
SCHEMBL4136726 0.67 MAPT (0.33) MAPT
SCHEMBL1021060 0.65 MAPT (0.56) MAOAMAOBMAPT
SCHEMBL1238056 0.64 MAPT (0.55) MAOAMAOBMAPT
SCHEMBL1237586 0.64 MAPT (0.70) MAOAMAOBMAPT
SCHEMBL1235852 0.62 MAPT (0.68) MAOAMAOBMAPT
SCHEMBL3397911 0.62 MAPT (0.62) MAOAMAOBMAPT
SCHEMBL2778300 0.61 MAOA (0.38) MAOAMAOBMAPT
SCHEMBL7925325 0.59 MAOA (0.36) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2446026-B1 TRANSAMINASE REACTIONS CODEXIS INC (US) 2017-08-09 EP disclosed