Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19216374 | 0.81 | — | — | |
| SCHEMBL18708803 | 0.71 | CYP1A2 (0.34) | — | |
| SCHEMBL10105599 | 0.67 | — | — | |
| SCHEMBL19513022 | 0.65 | MAPT (0.59) | — | |
| SCHEMBL854883 | 0.62 | — | — | |
| SCHEMBL10133989 | 0.61 | — | — | |
| SCHEMBL15830015 | 0.61 | EGFR (0.35) | — | |
| SCHEMBL27408429 | 0.60 | ADORA3 (0.35) | — | |
| SCHEMBL23341813 | 0.59 | PDPK1 (0.36) | — | |
| SCHEMBL10116310 | 0.59 | GPR119 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240451-B1 | Isoquinolinone derivatives substituted with a purine useful as PI3K inhibitors | INTELLIKINE LLC (US) | 2017-08-09 | — | — | EP | disclosed |