SCHEMBL1921634

SCHEMBL1921634

CCCCCCC1(CCCCCC)c2ccccc2-c2ccc(Cl)cc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 6/20 0.43
PGR P06401 2/20 0.41
AKR1A1 P14550 1/20 0.40
AKR1B1 P15121 1/20 0.40
MMP2 P08253 2/20 0.38
MMP9 P14780 2/20 0.38
MMP8 P22894 2/20 0.38
MMP13 P45452 2/20 0.38
APEX1 P27695 1/20 0.37
MEN1 O00255 2/20 0.35
APAF1 O14727 2/20 0.35
USP2 O75604 2/20 0.35
POLB P06746 2/20 0.35
HSP90AA1 P07900 2/20 0.35
MC4R P32245 2/20 0.35
UBE2N P61088 2/20 0.35
KMT2A Q03164 2/20 0.35
RCE1 Q9Y256 1/20 0.35
MAPT P10636 1/20 0.35
RAD52 P43351 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1920734 1.00 PDK2 (0.43) PDK2PGRAKR1A1AKR1B1MMP2
SCHEMBL1921910 0.94 PDK2 (0.45) PDK2PGRAKR1A1AKR1B1APEX1
SCHEMBL13708991 0.92 PDK2 (0.40) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL29590106 0.92 PDK2 (0.40) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL196478 0.92 PDK2 (0.40) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL196824 0.92 PDK2 (0.40) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL197162 0.92 PDK2 (0.40) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL29590107 0.92 PDK2 (0.40) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL20927642 0.90 PDK2 (0.39) PDK2PGRAKR1A1AKR1B1MMP2
SCHEMBL20927639 0.90 PDK2 (0.39) PDK2PGRAKR1A1AKR1B1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104540871-B The preparation method of aromatic compound 住友化学株式会社 2016-08-24 CN disclosed
EP-2327739-B1 Novel triarylamine polymer, process for its production and its use TOSOH CORP (JP) 2014-05-07 EP disclosed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed