SCHEMBL196824

SCHEMBL196824

CCCCCCC1(CCCCCC)c2cc(Cl)ccc2-c2ccc(Cl)cc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.40
AKR1A1 P14550 1/20 0.36
AKR1B1 P15121 1/20 0.36
MMP2 P08253 2/20 0.36
MMP9 P14780 2/20 0.36
MMP8 P22894 2/20 0.36
MMP13 P45452 2/20 0.36
HTR7 P34969 2/20 0.35
KCNH2 Q12809 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CNR1 P21554 2/20 0.34
CNR2 P34972 1/20 0.34
PSEN1 P49768 1/20 0.34
PSEN2 P49810 1/20 0.34
APH1B Q8WW43 1/20 0.34
NCSTN Q92542 1/20 0.34
APH1A Q96BI3 1/20 0.34
PSENEN Q9NZ42 1/20 0.34
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196478 1.00 PDK2 (0.40) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL197162 1.00 PDK2 (0.40) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL13708991 1.00 PDK2 (0.40) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL29590107 1.00 PDK2 (0.40) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL29590106 1.00 PDK2 (0.40) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL1921816 0.93 PDK2 (0.42) PDK2AKR1A1AKR1B1HTR7SMN1; SMN2
SCHEMBL1921634 0.92 PDK2 (0.43) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL1920734 0.92 PDK2 (0.43) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL16407235 0.92 CNR1 (0.36) PDK2AKR1A1AKR1B1MMP2MMP9
SCHEMBL196788 0.91 PDK2 (0.34) PDK2AKR1A1AKR1B1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110003271-B Process for producing aromatic compound 住友化学株式会社 2022-05-03 CN disclosed
US-11045796-B2 Process for producing aromatic compound, and palladium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-29 US disclosed
CN-108368142-B Method for producing aromatic compound and palladium complex 住友化学株式会社 2021-02-19 CN disclosed
US-20180369799-A1 PROCESS FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-12-27 US disclosed
EP-3385270-A1 METHOD FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX Sumitomo Chemical Company, Ltd (JP) 2018-10-10 EP disclosed
EP-2871199-B1 METHOD FOR PRODUCING AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2018-02-21 EP disclosed
EP-2871198-B1 METHOD FOR PRODUCING AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2017-06-14 EP disclosed
US-9453103-B2 Method for producing aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-09-27 US disclosed
CN-104540871-B The preparation method of aromatic compound 住友化学株式会社 2016-08-24 CN disclosed
US-9238665-B2 Method for producing aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-01-19 US disclosed
US-6362310-B1 LIGHT EMITTING POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-26 US disclosed
US-20010053842-A1 2,7-aryl-9-substituted fluorenes and 9-substituted fluorene oligomers and polymers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-12-20 US disclosed
US-6255449-B1 PROCESS FOR PREPARING POLYMERS HAVING AT LEAST THREE FLUORENE GROUPS IN BACKBONE, WHICH COMPRISES HEATING 2,7-DIHALO-9-SUBSTITUTED FLUORENES UNDER REACTION CONDITIONS SUFFICIENT TO FORM SAID POLYMERS THE DOW CHEMICAL COMPANY 2001-07-03 US disclosed
US-6255447-B1 OLIGOMERS OR POLYMERS WHICH DEMONSTRATE FLUORESCENCE, HIGH GLASS TRANSITION TEMPERATURES OR LIQUID-CRYSTALLINE PROPERTIES; FACILITATE PREPARATION OF FILMS HAVING HIGH HEAT RESISTANCE AND SOLVENT RESISTANCE THE DOW CHEMICAL COMPANY 2001-07-03 US disclosed
US-6169163-B1 NOVEL 2,7-DIHALOFLUORENES SUBSTITUTED AT 9-POSITION THE DOW CHEMICAL COMPANY 2001-01-02 US disclosed
EP-0842208-B1 2,7-ARYL-9-SUBSTITUTED FLUORENES AND 9-SUBSTITUTED FLUORENE OLIGOMERS AND POLYMERS DOW CHEMICAL CO (US) 2000-05-17 EP disclosed
US-5962631-A 2, 7-aryl-9-substituted fluorenes and 9-substituted fluorene oligomers and polymers THE DOW CHEMICAL COMPANY (US) 1999-10-05 US disclosed
EP-0842208-A1 2,7-ARYL-9-SUBSTITUTED FLUORENES AND 9-SUBSTITUTED FLUORENE OLIGOMERS AND POLYMERS THE DOW CHEMICAL COMPANY (US) 1998-05-20 EP disclosed
US-5708130-A 2,7-aryl-9-substituted fluorenes and 9-substituted fluorene oligomers and polymers THE DOW CHEMICAL COMPANY (US) 1998-01-13 US disclosed
WO-1997005184-A1 2,7-ARYL-9-SUBSTITUTED FLUORENES AND 9-SUBSTITUTED FLUORENE OLIGOMERS AND POLYMERS THE DOW CHEMICAL COMPANY (US) 1997-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11045796-B2 Process for producing aromatic compound, and palladium complex DDT, DRD1, DRD2 PDK2 140/4885AKR1A1 1459/4885AKR1B1 1178/4885
US-20180369799-A1 PROCESS FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX DDT, DRD1, DRD2 PDK2 140/4885AKR1A1 1459/4885AKR1B1 1178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.