SCHEMBL1921910

SCHEMBL1921910

CCCCC1(CCCC)c2ccccc2-c2ccc(Cl)cc21

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 9/20 0.45
PGR P06401 2/20 0.43
AKR1A1 P14550 1/20 0.41
AKR1B1 P15121 1/20 0.41
APEX1 P27695 1/20 0.39
MDM2 Q00987 1/20 0.35
S100A4 P26447 1/20 0.35
ELANE P08246 1/20 0.35
GPR3 P46089 1/20 0.34
HTR7 P34969 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1920734 0.94 PDK2 (0.43) PDK2PGRAKR1A1AKR1B1APEX1
SCHEMBL1921634 0.94 PDK2 (0.43) PDK2PGRAKR1A1AKR1B1APEX1
SCHEMBL1921816 0.92 PDK2 (0.42) PDK2PGRAKR1A1AKR1B1S100A4
SCHEMBL29590106 0.85 PDK2 (0.40) PDK2AKR1A1AKR1B1HTR7
SCHEMBL196478 0.85 PDK2 (0.40) PDK2AKR1A1AKR1B1HTR7
SCHEMBL196824 0.85 PDK2 (0.40) PDK2AKR1A1AKR1B1HTR7
SCHEMBL13708991 0.85 PDK2 (0.40) PDK2AKR1A1AKR1B1HTR7
SCHEMBL29590107 0.85 PDK2 (0.40) PDK2AKR1A1AKR1B1HTR7
SCHEMBL197162 0.85 PDK2 (0.40) PDK2AKR1A1AKR1B1HTR7
SCHEMBL1394531 0.85 APEX1 (0.50) PDK2PGRAPEX1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2327739-B1 Novel triarylamine polymer, process for its production and its use TOSOH CORP (JP) 2014-05-07 EP disclosed
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed