SCHEMBL19216883

SCHEMBL19216883

C=C(/C=C(\NC)c1ccc(-c2ccccc2)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.40
MAPT P10636 3/20 0.40
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
WDR5 P61964 1/20 0.36
CDC25B P30305 1/20 0.36
ATM Q13315 1/20 0.36
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
ERCC5 P28715 1/20 0.35
FEN1 P39748 1/20 0.35
HAO1 Q9UJM8 1/20 0.35
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23432039 0.89 MEN1 (0.37) SMN1; SMN2MAPTATMALDH1A1
SCHEMBL23049465 0.79 KMT2A (0.31)
SCHEMBL14979466 0.78 WDR5 (0.47) SMN1; SMN2MAPTNPC1RAB9ACTDSP1
SCHEMBL19139623 0.77 SMN1; SMN2 (0.48) SMN1; SMN2MAPTNPC1RAB9ACTDSP1
SCHEMBL23193036 0.76 NFE2L2 (0.38) SMN1; SMN2MAPTATMALDH1A1
SCHEMBL19139418 0.73 MEN1 (0.44) SMN1; SMN2MAPTNPC1RAB9AALDH1A1
SCHEMBL4536993 0.68 TDP1 (0.45) SMN1; SMN2MAPTNPC1RAB9AL3MBTL1
SCHEMBL4536997 0.68 TDP1 (0.45) SMN1; SMN2MAPTNPC1RAB9AL3MBTL1
SCHEMBL4536988 0.68 TDP1 (0.45) SMN1; SMN2MAPTNPC1RAB9AL3MBTL1
SCHEMBL11257027 0.68 SMN1; SMN2 (0.47) SMN1; SMN2MAPTNPC1RAB9ACTDSP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3202872-A1 ORGANIC LIGHT EMITTING ELEMENT LG Chem, Ltd. (KR) 2017-08-09 EP disclosed