SCHEMBL19217641

SCHEMBL19217641

Cc1ccc(-c2nc(C)ccc2C)c(C)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.45
CCR1 P32246 2/20 0.37
RAB9A P51151 1/20 0.37
CCR5 P51681 1/20 0.37
NSD2 O96028 2/20 0.36
G6PD P11413 2/20 0.36
DNMT1 P26358 2/20 0.36
OPRK1 P41145 1/20 0.35
KMT2A Q03164 1/20 0.35
NOS3 P29474 1/20 0.33
NOS1 P29475 1/20 0.33
NOS2 P35228 1/20 0.33
BRAF P15056 1/20 0.33
CYP1A2 P05177 3/20 0.32
CYP2C19 P33261 1/20 0.32
CCR8 P51685 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GRIA2 P42262 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13825779 0.80 CCR1 (0.48) S100A4CCR1RAB9ACCR5NSD2
SCHEMBL26155339 0.77 CYP1A2 (0.45) S100A4RAB9AKMT2ACYP1A2KDM4E
SCHEMBL24066436 0.76 ADORA2A (0.44) S100A4RAB9AKMT2ACYP1A2CYP2C19
SCHEMBL29504006 0.75
SCHEMBL82917 0.75
SCHEMBL19607596 0.74 CYP1A2 (0.47) S100A4CCR1RAB9ACCR5KMT2A
SCHEMBL26232902 0.72 CYP1A2 (0.45) RAB9AKMT2ACYP1A2KDM4EMAPT
SCHEMBL24394983 0.72 NUDT1 (0.42) S100A4CCR1NOS3NOS2CCR8
SCHEMBL21982341 0.71 NPC1 (0.42) RAB9ACYP1A2CYP2C19ALDH1A1
SCHEMBL24404852 0.70 S100A4 (0.43) S100A4CCR1RAB9ACCR5NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9728730-B2 Compound for organic optoelectric device and composition and organic optoelectric device and display device SAMSUNG SDI CO., LTD. (KR) 2017-08-08 US disclosed