SCHEMBL19220230

SCHEMBL19220230

CCNC(=O)N1CCCC(NS(C)(=O)=O)C1CO[C@H]1CC[C@@H](c2ccccc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ HCRTR2 O43614 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19219920 1.00 HCRTR2 (1.00) HCRTR2
SCHEMBL24284431 0.95 HCRTR2 (1.00) HCRTR2
SCHEMBL19222762 0.95 HCRTR2 (1.00) HCRTR2
SCHEMBL22355739 0.94 HCRTR2 (0.89) HCRTR2
SCHEMBL22346089 0.94 HCRTR2 (0.89) HCRTR2
SCHEMBL19220023 0.93 HCRTR2 (1.00) HCRTR2
SCHEMBL19220005 0.93 HCRTR2 (1.00) HCRTR2
SCHEMBL19222990 0.91 HCRTR2 (1.00) HCRTR2
SCHEMBL19222829 0.90 HCRTR2 (1.00) HCRTR2
SCHEMBL19222776 0.90 HCRTR2 (1.00) HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260001843-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICALS CO (JP) 2026-01-01 — — US disclosed
US-12281073-B2 Substituted piperidine compound and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-04-22 — — US disclosed
US-20240174610-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-05-30 — — US disclosed
US-11292766-B2 Substituted piperidine compound and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (US) 2022-04-05 — — US disclosed
US-20220081399-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-03-17 — — US disclosed
US-20200115399-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-04-16 — — US disclosed
US-20190263843-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-08-29 — — US disclosed
US-10287305-B2 Substituted piperidine compound and use thereof TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-05-14 — — US disclosed
US-20190031611-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-01-31 — — US disclosed
US-20170226137-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-08-10 — — US disclosed
US-20170226137-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-08-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220081399-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF HCRTR2, HCRTR1, NTSR2 HCRTR2 1/4885
US-20240174610-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF HCRTR2, HCRTR1, NTSR2 HCRTR2 1/4885
US-20190263843-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF HCRTR2, HCRTR1, NTSR2 HCRTR2 1/4885
US-12281073-B2 Substituted piperidine compound and use thereof HCRTR2, HCRTR1, NTSR2 HCRTR2 1/4885
US-11292766-B2 Substituted piperidine compound and use thereof HCRTR2, HCRTR1, NTSR2 HCRTR2 1/4885
US-20260001843-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF HCRTR2, HCRTR1, NPBWR1 HCRTR2 1/4885
US-20170226137-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF HCRTR2, HCRTR1, NTSR2 HCRTR2 1/4885
US-20200115399-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF HCRTR2, HCRTR1, NTSR2 HCRTR2 1/4885
US-20190031611-A1 SUBSTITUTED PIPERIDINE COMPOUND AND USE THEREOF HCRTR2, HCRTR1, NTSR2 HCRTR2 1/4885
US-10287305-B2 Substituted piperidine compound and use thereof HCRTR2, HCRTR1, NTSR2 HCRTR2 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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