SCHEMBL19220482

SCHEMBL19220482

C[Si](C)(C)O[Si](O[Si](O)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
NR1H2 P55055 2/20 0.33
NR1H3 Q13133 2/20 0.33
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2919242 0.89 ESR1 (0.33) ESR1ESR2NR1H2NR1H3
SCHEMBL4620122 0.87 ESR1 (0.32) ESR1ESR2
SCHEMBL11716671 0.87 ESR1 (0.32) ESR1ESR2
SCHEMBL8972492 0.87 ESR1 (0.41) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL94228 0.87 ESR1 (0.39) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL14580298 0.86 ESR1 (0.39) ESR1ESR2NR1H2NR1H3
SCHEMBL26427810 0.86 ESR1 (0.38) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL8992173 0.85 ESR1 (0.38) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL16521498 0.85 ESR1 (0.38) ESR1ESR2NR1H2NR1H3MAPT
SCHEMBL19220477 0.85 ESR1 (0.34) ESR1ESR2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170226386-A1 SURFACE PROTECTIVE FILM, MAKING METHOD, AND SUBSTRATE PROCESSING LAMINATE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-10 US disclosed