Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 7/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 7/20 | 0.55 |
| ▸ | RELA | Q04206 | 7/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15704340 | 0.91 | NFKB1 (0.54) | NFKB1NFKB2RELADPP4ESR1 | |
| SCHEMBL14249292 | 0.81 | NFKB1 (0.78) | NFKB1NFKB2RELADPP4ESR1 | |
| SCHEMBL14249291 | 0.81 | NFKB1 (0.78) | NFKB1NFKB2RELADPP4ESR1 | |
| Xanthohumol B SCHEMBL12961703 | 0.78 | NFKB1 (0.56) | NFKB1NFKB2RELADPP4ESR1 | |
| Xanthohumol B SCHEMBL29934961 | 0.78 | NFKB1 (0.56) | NFKB1NFKB2RELADPP4ESR1 | |
| Xanthohumol C SCHEMBL30066955 | 0.76 | NFKB1 (0.65) | NFKB1NFKB2RELADPP4ESR1 | |
| Xanthohumol C SCHEMBL14249680 | 0.76 | NFKB1 (0.65) | NFKB1NFKB2RELADPP4ESR1 | |
| Xanthohumol C SCHEMBL12961704 | 0.76 | NFKB1 (0.65) | NFKB1NFKB2RELADPP4ESR1 | |
| SCHEMBL31398714 | 0.74 | NFKB1 (0.83) | NFKB1NFKB2RELADPP4TDP1 | |
| SCHEMBL4834940 | 0.72 | TDP1 (0.83) | NFKB1NFKB2RELADPP4ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202398-A1 | CHROMANE-LIKE CYCLIC PRENYLFLAVONOIDS FOR THE MEDICAL INTERVENTION IN NEUROLOGICAL DISORDERS | Aigner, Ludwig (DE) | 2017-08-09 | — | — | EP | disclosed |