Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 7/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | LATS1 | O95835 | 3/20 | 0.40 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15388907 | 0.93 | PDPK1 (0.51) | L3MBTL1PDPK1HTR6DRD2HTR2A | |
| SCHEMBL30461646 | 0.77 | HTR6 (0.61) | L3MBTL1PDPK1HTR6CA2CA9 | |
| SCHEMBL25422336 | 0.77 | HTR6 (0.61) | L3MBTL1PDPK1HTR6CA2CA9 | |
| SCHEMBL12501042 | 0.73 | PDPK1 (0.68) | PDPK1HTR6DRD2HTR2AHTR7 | |
| SCHEMBL30461607 | 0.72 | DYRK1B (0.48) | L3MBTL1PDPK1HTR6DRD2HTR2A | |
| SCHEMBL25420973 | 0.72 | DYRK1A (0.55) | L3MBTL1PDPK1HTR6CA2CA9 | |
| SCHEMBL25422412 | 0.72 | DYRK1B (0.48) | L3MBTL1PDPK1HTR6DRD2HTR2A | |
| SCHEMBL25420439 | 0.72 | HTR6 (0.51) | L3MBTL1HTR6CA2CA9KDM4E | |
| SCHEMBL12450003 | 0.72 | HTR6 (0.51) | L3MBTL1PDPK1HTR6CA2CA9 | |
| SCHEMBL30461713 | 0.72 | HTR6 (0.51) | L3MBTL1HTR6CA2CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725446-B2 | 7-azaindole derivatives | MERCK PATENT GMBH (DE) | 2017-08-08 | — | — | US | disclosed |