Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30461713 | 1.00 | HTR6 (0.51) | HTR6KDM4EUBE2NCA2CA9 | |
| SCHEMBL30975059 | 0.89 | HTR6 (0.61) | HTR6KDM4EUBE2NCA2CA9 | |
| SCHEMBL254249 | 0.86 | HTR6 (0.52) | HTR6 | |
| SCHEMBL12450003 | 0.84 | HTR6 (0.51) | HTR6KDM4EUBE2NCA2CA9 | |
| SCHEMBL30461646 | 0.82 | HTR6 (0.61) | HTR6KDM4EUBE2NCA2CA9 | |
| SCHEMBL25422336 | 0.82 | HTR6 (0.61) | HTR6KDM4EUBE2NCA2CA9 | |
| SCHEMBL5429439 | 0.80 | KDM4E (0.68) | HTR6KDM4EUBE2NCA2CA9 | |
| SCHEMBL31315848 | 0.80 | KDM4E (0.49) | HTR6KDM4EUBE2NCA2L3MBTL1 | |
| SCHEMBL29414758 | 0.80 | KDM4E (0.68) | HTR6KDM4EUBE2NCA2CA9 | |
| SCHEMBL16608384 | 0.78 | L3MBTL1 (0.44) | HTR6KDM4EUBE2NCA2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107722-A1 | COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107722-A1 | COMPOUNDS FOR USE IN TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |