Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19774465 | 0.88 | MTNR1A (0.62) | CYP1A2CYP3A4CYP2D6LTA4H | |
| SCHEMBL5182644 | 0.82 | PLAAT3 (0.58) | ATMKDM4EPOLBCYP19A1CA2 | |
| SCHEMBL30869991 | 0.80 | ATM (0.70) | ATMKDM4EPOLBCYP19A1CA2 | |
| SCHEMBL10343404 | 0.80 | ATM (0.70) | ATMKDM4EPOLBCYP19A1CA2 | |
| SCHEMBL2224074 | 0.80 | ATM (0.61) | ATMKDM4EPOLBCYP19A1CA2 | |
| SCHEMBL503571 | 0.79 | PLAAT3 (0.61) | ATMKDM4ECA2PLAAT3PLAAT5 | |
| Water SCHEMBL11279881 | 0.79 | ATM (0.59) | ATMKDM4EPOLBCYP19A1CA2 | |
| SCHEMBL23913120 | 0.79 | ATM (0.68) | ATMKDM4EPOLBCYP19A1CA2 | |
| SCHEMBL31556187 | 0.79 | ATM (0.68) | ATMKDM4EPOLBCYP19A1CA2 | |
| SCHEMBL31556190 | 0.79 | ATM (0.68) | ATMKDM4EPOLBCYP19A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855586-B1 | FLAME RETARDANT POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE THEREOF AND ARTICLES COMPRISING THE SAME | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2017-08-09 | — | — | EP | disclosed |