Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TK1 | P04183 | 4/20 | 0.36 |
| ▸ | TYMP | P19971 | 2/20 | 0.36 |
| ▸ | TK2 | O00142 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19227501 | 1.00 | TOP2A (0.39) | TOP2AALDH1A1LMNAALBPOLB | |
| SCHEMBL2708335 | 0.88 | TOP2A (0.41) | TOP2AALDH1A1LMNAALBPOLB | |
| SCHEMBL12180655 | 0.87 | TK1 (0.38) | TOP2AALDH1A1LMNAALBPOLB | |
| SCHEMBL14828583 | 0.87 | TK1 (0.38) | TOP2AALDH1A1LMNAALBPOLB | |
| SCHEMBL10211912 | 0.86 | TYMP (0.40) | TOP2AALDH1A1LMNAALBPOLB | |
| SCHEMBL14827493 | 0.85 | ALDH1A1 (0.42) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL12286955 | 0.85 | TYMP (0.48) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL13379950 | 0.85 | TK1 (0.42) | TOP2AALDH1A1LMNAALBPOLB | |
| SCHEMBL4405133 | 0.85 | TYMP (0.48) | ALDH1A1LMNAALBPOLBADRA1A | |
| SCHEMBL19227589 | 0.85 | TYMP (0.48) | ALDH1A1LMNAALBPOLBADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725479-B2 | 5′-end derivatives | IONIS PHARMACEUTICALS, INC. (US) | 2017-08-08 | — | — | US | disclosed |