Quinacrine

Quinacrine

SCHEMBL19225

CCN(CC)CCCC(C)Nc1c2ccc(Cl)cc2nc2ccc(OC)cc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 4/20 1.00
TP53 P04637 3/20 1.00
CYP3A4 P08684 3/20 1.00
CASP1 P29466 3/20 1.00
CASP7 P55210 3/20 1.00
HBB P68871 3/20 1.00
HSD17B10 Q99714 3/20 1.00
CYP1A2 P05177 2/20 1.00
CYP2D6 P10635 2/20 1.00
TSHR P16473 2/20 1.00
BRCA1 P38398 2/20 1.00
HIF1A Q16665 2/20 1.00
NPC1 O15118 1/20 1.00
PRNP P04156 1/20 1.00
CHRM2 P08172 1/20 1.00
CHRM4 P08173 1/20 1.00
ABCB1 P08183 1/20 1.00
HTR1A P08908 1/20 1.00
CHRM5 P08912 1/20 1.00
ADRA2A P08913 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinacrine SCHEMBL29363141 1.00 USP2 (1.00) USP2TP53CYP3A4CASP1CASP7
Quinacrine SCHEMBL20205 1.00 USP2 (1.00) USP2TP53CYP3A4CASP1CASP7
Quinacrine SCHEMBL29717736 1.00 USP2 (1.00) USP2TP53CYP3A4CASP1CASP7
Quinacrine SCHEMBL17704776 1.00 USP2 (1.00) USP2TP53CYP3A4CASP1CASP7
Quinacrine SCHEMBL1817364 1.00 USP2 (1.00) USP2TP53CYP3A4CASP1CASP7
Quinacrine SCHEMBL33693 0.99 USP2 (1.00) USP2TP53CYP3A4CASP1CASP7
Quinacrine SCHEMBL30153780 0.99 USP2 (1.00) USP2TP53CYP3A4CASP1CASP7
Quinacrine SCHEMBL15061349 0.99 USP2 (1.00) USP2TP53CYP3A4CASP1CASP7
Quinacrine SCHEMBL162379 0.99 USP2 (1.00) USP2TP53CYP3A4CASP1CASP7
Quinacrine SCHEMBL28651594 0.99 USP2 (0.98) USP2TP53CYP3A4CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 21778 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137806-A1 INTERCALATING SUGAR MOLECULES XALUD THERAPEUTICS, INC. (US) 2026-05-21 US claimed
CN-122056884-A Methods of treating pancreatic cancer 坎莫森特里克斯公司 2026-05-19 CN claimed
US-20260130998-A1 TREATMENT OF AUTOIMMUNE DISORDERS USING CHIMERIC ANTIGEN RECEPTOR THERAPY NOVARTIS AG (CH) 2026-05-14 US claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
US-20260108476-A1 2,4 DNP and Prodrugs Thereof for Treatment of Cancer MITOCHON PHARMACEUTICALS, INC. (US) 2026-04-23 US claimed
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CELLIS AG (CH) 2026-04-02 US claimed
US-12569371-B2 Sterilization of medical dressings with enhanced antimicrobial properties HYDROFERA, LLC (US) 2026-03-10 US claimed
US-12550885-B2 Red blood cell storage solutions, solution additives, and methods for improving the storage of red blood cells UNIVERSITY OF CINCINNATI (US) 2026-02-17 US claimed
US-12548678-B2 Methods and systems for machine learning analysis of single nucleotide polymorphisms in lupus AMPEL BIOSOLUTIONS, LLC (US) 2026-02-10 US claimed
US-20260014092-A1 EXTRACELLULAR VESICLES FROM MICROALGAE, THEIR USE FOR VACCINES AND FOR IMMUNOMODULATION AGS THERAPEUTICS SAS (FR) 2026-01-15 US claimed
EP-0035856-B1 PHARMACEUTICAL AND DIETARY COMPOSITIONS EFAMOL LIMITED (GB) 1984-07-04 EP claimed
EP-0108588-A2 Plasma-free medium for platelet storage and its production Rock, Gail Ann (CA) 1984-05-16 EP claimed
US-4447415-A REMOVING PLASMA; RESUSPENDING PLATELETS IN ISOTONIC SOLUTION ROCK GAIL A 1984-05-08 US claimed
EP-0003583-B1 COMPOSITIONS FOR CYTOCHEMICAL INVESTIGATION, THEIR USE AND METHOD FOR THE DETECTION OF STEROID HORMONE RECEPTORS IN HUMAN TISSUES Lee, Sin Hang (US) 1981-12-02 EP claimed
EP-0037175-A1 Pharmaceutical compositions EFAMOL LIMITED (GB) 1981-10-07 EP claimed
EP-0035856-A2 Pharmaceutical and dietary compositions EFAMOL LIMITED (GB) 1981-09-16 EP claimed
US-4215102-A Cytochemical agents and methods for the detection of steroid hormone receptors in human tissues LEE SIN H 1980-07-29 US claimed
US-4185618-A Promotion of fibrous tissue growth in fallopian tubes for female sterilization POPULATION RESEARCH, INC. (US) 1980-01-29 US claimed
US-4181725-A BROMOPHENACYL BROMIDE, TOCOPHEROL, MEPACRINE, (HYDROXY)CHLOROQUINE, DIBUCAINE, TETRACAINE, LIDOCAINE, BUTACAINE, PROCAINE, EDTA THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 1980-01-01 US claimed
EP-0003583-A1 Compositions for cytochemical investigation, their use and method for the detection of steroid hormone receptors in human tissues Lee, Sin Hang (US) 1979-08-22 EP claimed