Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839393 | 0.90 | GPR119 (0.46) | GPR119MAOAMAOBBCHEACHE | |
| SCHEMBL4403110 | 0.88 | MAOB (0.44) | GPR119MAOAMAOBBCHEACHE | |
| SCHEMBL1296310 | 0.88 | GPR119 (0.63) | GPR119 | |
| SCHEMBL2561511 | 0.87 | GPR119 (0.61) | GPR119 | |
| SCHEMBL1841877 | 0.85 | GPR119 (0.47) | GPR119HRH3 | |
| SCHEMBL1922551 | 0.84 | GPR119 (0.44) | GPR119MAOAMAOBBCHEACHE | |
| SCHEMBL1841876 | 0.84 | GPR119 (0.42) | GPR119MAOAMAOBBCHEACHE | |
| SCHEMBL12103493 | 0.83 | ITGB3 (0.53) | — | |
| SCHEMBL2431556 | 0.83 | GPR119 (0.63) | GPR119CYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL1296299 | 0.82 | ITGB3 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328867-A1 | HETEROCYCLIC GPCR AGONISTS | Prosidion Limited (GB) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010004347-A1 | HETEROCYCLIC GPCR AGONISTS | PROSIDION LIMITED (GB) | 2010-01-14 | — | — | WO | disclosed |