Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 12/20 | 0.48 |
| ▸ | F2 | P00734 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19225969 | 0.91 | CFD (0.46) | CFD | |
| SCHEMBL19225901 | 0.91 | CFD (0.46) | CFD | |
| SCHEMBL19225971 | 0.86 | CFD (0.48) | CFD | |
| SCHEMBL19226066 | 0.86 | CFD (0.47) | CFDF2 | |
| SCHEMBL19226055 | 0.85 | CFD (0.48) | CFD | |
| SCHEMBL19226078 | 0.85 | CFD (0.46) | CFDF2 | |
| SCHEMBL19225837 | 0.85 | CFD (0.48) | CFDALDH1A1 | |
| SCHEMBL19225957 | 0.83 | CFD (0.47) | CFD | |
| SCHEMBL19226083 | 0.83 | CFD (0.39) | CFDF2ALDH1A1 | |
| SCHEMBL19225894 | 0.82 | CFD (0.47) | CFDF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867225-B1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2017-08-09 | — | — | EP | disclosed |