Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 8/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 10/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19225966 | 0.90 | CFD (0.50) | CFDMMP13 | |
| SCHEMBL19225861 | 0.88 | CFD (0.47) | CFD | |
| SCHEMBL15602024 | 0.88 | CFD (0.47) | CFD | |
| SCHEMBL19225878 | 0.82 | ELANE (0.33) | CFD | |
| SCHEMBL19225888 | 0.80 | CFD (0.38) | CFD | |
| SCHEMBL19226053 | 0.78 | CFD (0.41) | CFD | |
| SCHEMBL15602027 | 0.77 | CFD (0.50) | CFDMMP13 | |
| SCHEMBL15602018 | 0.77 | CFD (0.47) | CFD | |
| SCHEMBL19225837 | 0.76 | CFD (0.48) | CFDMMP13 | |
| SCHEMBL19225969 | 0.76 | CFD (0.46) | CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867225-B1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2017-08-09 | — | — | EP | disclosed |