Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 6/20 | 0.38 |
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | CPA2 | P48052 | 1/20 | 0.35 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19225882 | 0.93 | CFD (0.40) | CFDNTMT1PSMB9FAPACE | |
| SCHEMBL19226053 | 0.89 | CFD (0.41) | CFDFAP | |
| SCHEMBL15602024 | 0.84 | CFD (0.47) | CFDFAP | |
| SCHEMBL19225861 | 0.84 | CFD (0.47) | CFDFAP | |
| SCHEMBL19225829 | 0.83 | CFD (0.41) | CFDFAP | |
| SCHEMBL19225827 | 0.82 | CFD (0.40) | CFDNTMT1ACEMEN1KMT2A | |
| SCHEMBL15602022 | 0.82 | CFD (0.42) | CFDFAP | |
| SCHEMBL15602018 | 0.80 | CFD (0.47) | CFDFAP | |
| SCHEMBL19225879 | 0.80 | CFD (0.49) | CFD | |
| SCHEMBL19225878 | 0.80 | ELANE (0.33) | CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2867225-B1 | PYRROLIDINE DERIVATIVES AND THEIR USE AS COMPLEMENT PATHWAY MODULATORS | NOVARTIS AG (CH) | 2017-08-09 | — | — | EP | disclosed |