Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL919807 | 0.87 | CYP2C19 (0.47) | CYP2C19CYP2C9MEN1KMT2ACYP1A2 | |
| SCHEMBL3971405 | 0.83 | NPC1 (0.56) | PPARANPC1RAB9A | |
| SCHEMBL2850028 | 0.78 | RIPK1 (0.49) | CYP2C19CYP2C9MEN1KMT2ACYP1A2 | |
| SCHEMBL12173763 | 0.76 | OPRM1 (0.46) | — | |
| SCHEMBL8626757 | 0.76 | OPRM1 (0.48) | — | |
| SCHEMBL919178 | 0.75 | SCN9A (0.47) | PPARAPPARG | |
| SCHEMBL3969644 | 0.73 | MAOB (0.57) | — | |
| SCHEMBL919039 | 0.73 | KMT2A (0.46) | CYP2C19CYP2C9MEN1KMT2ACYP1A2 | |
| SCHEMBL918991 | 0.73 | MAPK14 (0.50) | ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL9294968 | 0.72 | CYP2C9 (0.56) | CYP2C19CYP2C9MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202759-A1 | ALPHA-AMINOAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Korea Institute of Science and Technology (KR) | 2017-08-09 | — | — | EP | disclosed |