SCHEMBL1922752

SCHEMBL1922752

Cc1cccc(Nc2ccc(Nc3cccc(C)c3C)cc2)c1C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.59
TDP1 Q9NUW8 3/20 0.52
LMNA P02545 2/20 0.52
KMT2A Q03164 2/20 0.52
MEN1 O00255 1/20 0.52
AKR1B10 O60218 1/20 0.52
TRPA1 O75762 1/20 0.52
ABCB11 O95342 1/20 0.52
DHFR P00374 1/20 0.52
MPO P05164 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CHRM1 P11229 1/20 0.52
CYP2C9 P11712 1/20 0.52
AKR1B1 P15121 1/20 0.52
PTGS1 P23219 1/20 0.52
PTGS2 P35354 1/20 0.52
AKR1C3 P42330 1/20 0.52
AKR1C2 P52895 1/20 0.52
AKR1C1 Q04828 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7974336 0.94 RAPGEF4 (0.53) RAPGEF4TDP1LMNAKMT2AMEN1
SCHEMBL1922114 0.94 RAPGEF4 (0.53) RAPGEF4TDP1LMNAKMT2AMEN1
SCHEMBL29550941 0.92 TDP1 (0.54) RAPGEF4TDP1LMNAKMT2AMEN1
SCHEMBL22772445 0.92 TDP1 (0.54) RAPGEF4TDP1LMNAKMT2AMEN1
SCHEMBL30594032 0.91 MEN1 (0.58) RAPGEF4TDP1LMNAKMT2AMEN1
SCHEMBL429858 0.91 MEN1 (0.58) RAPGEF4TDP1LMNAKMT2AMEN1
SCHEMBL7974344 0.90 MAPT (0.55) RAPGEF4TDP1LMNAKMT2AMEN1
SCHEMBL27867786 0.90 RAPGEF4 (0.50) RAPGEF4TDP1LMNAKMT2AMEN1
SCHEMBL29402598 0.90 MAPT (0.55) RAPGEF4TDP1LMNAKMT2AMEN1
SCHEMBL28341981 0.90 RAPGEF4 (0.50) RAPGEF4TDP1LMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed
US-6274666-B1 COPOLYMER OF VINYL AROMATIC HYDROCARBON AND CONJUGATED DIENE BRIDGESTONE/FIRESTONE, INC. 2001-08-14 US disclosed
EP-0659787-B1 Block copolymers and high shear strength pressure sensitive adhesive compositions comprising them SHELL INT RESEARCH (NL) 2000-09-20 EP disclosed
US-6034206-A POLYANILINES; HEAT, CHEMICAL AND SOLVENT RESISTANCE TOSOH CORPORATION (JP) 2000-03-07 US disclosed
EP-0696603-B1 Improved adhesive and polymer for adhesives BRIDGESTONE FIRESTONE INC (US) 1999-10-13 EP disclosed
EP-0696603-A1 Improved adhesive and polymer for adhesives BRIDGESTONE/FIRESTONE, INC. (US) 1996-02-14 EP disclosed
EP-0659787-A1 Block copolymers and high shear strength pressure sensitive adhesive compositions comprising them SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1995-06-28 EP disclosed
EP-0243956-B1 ADHESIVE COMPOSITIONS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-12-11 EP disclosed
US-4792584-A BLOCK COPOLYMER OF BUTADIENE AND VINYL AROMATIC HYDROCARBON, TACKIFIER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-12-20 US disclosed
EP-0243956-A2 Adhesive compositions Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-11-04 EP disclosed
US-4256669-A SOLVENT EXTRACTION AND ALKYLATION WITH AROMATIC AMINE TO PRODUCE DIARYL PARA-PHENYLENEDIAMINES MALLINCKRODT, INC. (US) 1981-03-17 US disclosed
US-4224247-A Recovery of para-aminophenol MALLINCKRODT, INC. (US) 1980-09-23 US disclosed