SCHEMBL7974336

SCHEMBL7974336

Cc1ccccc1Nc1ccc(Nc2cccc(C)c2C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.53
TDP1 Q9NUW8 5/20 0.51
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
LMNA P02545 2/20 0.51
PTGS2 P35354 2/20 0.51
AKR1B10 O60218 1/20 0.51
TRPA1 O75762 1/20 0.51
ABCB11 O95342 1/20 0.51
DHFR P00374 1/20 0.51
MPO P05164 1/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CHRM1 P11229 1/20 0.51
CYP2C9 P11712 1/20 0.51
AKR1B1 P15121 1/20 0.51
PTGS1 P23219 1/20 0.51
AKR1C3 P42330 1/20 0.51
AKR1C2 P52895 1/20 0.51
AKR1C1 Q04828 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1922752 0.94 RAPGEF4 (0.59) RAPGEF4TDP1KMT2AMEN1LMNA
SCHEMBL29550941 0.90 TDP1 (0.54) RAPGEF4TDP1KMT2AMEN1LMNA
SCHEMBL22772445 0.90 TDP1 (0.54) RAPGEF4TDP1KMT2AMEN1LMNA
SCHEMBL30594032 0.89 MEN1 (0.58) RAPGEF4TDP1KMT2AMEN1LMNA
SCHEMBL429858 0.89 MEN1 (0.58) RAPGEF4TDP1KMT2AMEN1LMNA
SCHEMBL11403543 0.89 KMT2A (0.61) RAPGEF4TDP1KMT2AMEN1LMNA
SCHEMBL29653984 0.89 MAPT (0.54) TDP1KMT2AMEN1PTGS2PTGS1
SCHEMBL108882 0.89 MAPT (0.54) TDP1KMT2AMEN1PTGS2PTGS1
SCHEMBL1922114 0.88 RAPGEF4 (0.53) RAPGEF4TDP1KMT2AMEN1LMNA
SCHEMBL28916753 0.86 TDP1 (0.55) RAPGEF4TDP1KMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022048565-A1 PREPARATION METHOD FOR ASYMMETRIC DIARYL SUBSTITUTED P-PHENYLENEDIAMINE COMPOUND 圣奥化学科技有限公司 2022-03-10 WO disclosed
CN-104903430-A Composition comprising a metal oxide and a metal oxide SHELL INT RESEARCH 2015-09-09 CN disclosed
US-6274666-B1 COPOLYMER OF VINYL AROMATIC HYDROCARBON AND CONJUGATED DIENE BRIDGESTONE/FIRESTONE, INC. 2001-08-14 US disclosed
EP-0659787-B1 Block copolymers and high shear strength pressure sensitive adhesive compositions comprising them SHELL INT RESEARCH (NL) 2000-09-20 EP disclosed
EP-0696603-B1 Improved adhesive and polymer for adhesives BRIDGESTONE FIRESTONE INC (US) 1999-10-13 EP disclosed
EP-0696603-A1 Improved adhesive and polymer for adhesives BRIDGESTONE/FIRESTONE, INC. (US) 1996-02-14 EP disclosed
EP-0659787-A1 Block copolymers and high shear strength pressure sensitive adhesive compositions comprising them SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1995-06-28 EP disclosed
EP-0243956-B1 ADHESIVE COMPOSITIONS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-12-11 EP disclosed
US-4792584-A BLOCK COPOLYMER OF BUTADIENE AND VINYL AROMATIC HYDROCARBON, TACKIFIER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-12-20 US disclosed
EP-0243956-A2 Adhesive compositions Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-11-04 EP disclosed