SCHEMBL1922809

SCHEMBL1922809

CC(C)=[Zr](C)(C)c1c(C2=CC=CC2)ccc2c1Cc1ccccc1-2

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
PGR P06401 1/20 0.34
PNMT P11086 1/20 0.33
HTR2B P41595 2/20 0.32
CYP1A2 P05177 1/20 0.32
ADRA2A P08913 1/20 0.32
MAOA P21397 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2C P28335 1/20 0.32
SLC6A4 P31645 1/20 0.32
SRD5A2 P31213 1/20 0.32
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8896107 0.86 SRD5A2 (0.35) NPC1RAB9APGRPNMTSRD5A2
SCHEMBL8897776 0.85 NPC1 (0.36) NPC1RAB9APGRPNMTHTR2B
SCHEMBL6837572 0.84 PGR (0.35) NPC1RAB9APGRPNMTSRD5A2
Hydrochloric Acid SCHEMBL618234 0.83 PGR (0.34) NPC1RAB9APGRPNMTHTR2B
SCHEMBL8896051 0.81 NPC1 (0.33) NPC1RAB9APGRPNMTSRD5A2
SCHEMBL28220071 0.79 PNMT (0.44) NPC1RAB9APGRPNMTHTR2B
Hydrochloric Acid SCHEMBL6907081 0.79 PGR (0.33) NPC1RAB9APGRPNMTSRD5A2
Hydrochloric Acid SCHEMBL27425148 0.78 PNMT (0.42) NPC1RAB9APGRPNMTHTR2B
SCHEMBL27348144 0.77 PNMT (0.45) NPC1RAB9APGRPNMTHTR2B
SCHEMBL698266 0.76 NPC1 (0.39) NPC1RAB9APGRPNMTHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0426638-B2 Addition of aluminium alkyl for improved metallocene catalyst FINA TECHNOLOGY (US) 2005-03-02 EP claimed
JP-3179005-A None JP disclosed
US-8524627-B2 Activating supports with controlled distribution of OH groups TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2013-09-03 US disclosed
EP-2328939-B1 ACTIVATING SUPPORTS BASED ON PERFLUORINATED BORONIC ACIDS TOTAL RES & TECHNOLOGY FELUY (BE) 2012-12-12 EP disclosed
US-20120101239-A1 ACTIVATING SUPPORTS WITH CONTROLLED DISTRIBUTION OF OH GROUPS CENTRE NATIONAL DE LA RESCHERCHE SCIENTIFIQUE (FR) 2012-04-26 US disclosed
EP-2328939-A1 ACTIVATING SUPPORTS BASED ON PERFLUORINATED BORONIC ACIDS Total Petrochemicals Research Feluy (BE) 2011-06-08 EP disclosed
EP-2251362-A1 Activating supports with controlled distribution of OH groups TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2010-11-17 EP disclosed
US-7759271-B2 Activating supports for metallocene catalysis TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2010-07-20 US disclosed
WO-2010037808-A1 ACTIVATING SUPPORTS BASED ON PERFLUORINATED BORONIC ACIDS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2010-04-08 WO disclosed
EP-2172493-A1 Activating supports based on perfluorinated boronic acids TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2010-04-07 EP disclosed
EP-0619326-B1 Olefin polymerization catalyst and olefin polymerisation process TOSOH CORP (JP) 1997-06-25 EP disclosed
US-5574100-A ALPHA-OLEFIN-CYCLIC OLEFIN COPOLYMER, BUTADIENE-STYRENE COPOLYMER CORE, ALICYCLIC ACRYLATE SHELL MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-11-12 US disclosed
US-5567777-A CONTAINING AN ALPHA-OLEFIN; TRANSPARENCY MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-10-22 US disclosed
US-5567776-A BLEND ELASTOMERIC COPOLYMERS CONTAINING ALPHA- AND CYCLO-OLEFINS; IMPACT STRENGTH, TRANSPARENCY, FIBER OPTICS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-10-22 US disclosed
US-5494969-A IMPACT STRENGTH, TRANSPARENCY, HEAT RESISTANCE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1996-02-27 US disclosed
EP-0671433-A1 Polymer composition and core-shell elastomer used therefor MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-09-13 EP disclosed
EP-0619326-A1 Olefin polymerization catalyst and olefin polymerisation process TOSOH CORPORATION (JP) 1994-10-12 EP disclosed
EP-0608903-A1 Cycloolefin polymer composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-08-03 EP disclosed
EP-0597119-A1 CYCLOOLEFIN COPOLYMER COMPOSITION AND PRODUCTION THEREOF MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-05-18 EP disclosed
JP-H03179005-A METALLOCENE CATALYST FINA TECHNOL INC 1991-08-05 JP disclosed