SCHEMBL19230397

SCHEMBL19230397

CN1C(=O)C(=O)c2c1ccc1c2ccc2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPRT1 P00492 3/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
CYP2D6 P10635 1/20 0.45
HPGD P15428 1/20 0.45
ALOX12 P18054 1/20 0.45
MAPK1 P28482 1/20 0.45
HIF1A Q16665 1/20 0.45
CES1 P23141 2/20 0.43
TTR P02766 1/20 0.43
PAX8 Q06710 1/20 0.43
CYP2A6 P11509 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19230422 0.92 CES1 (0.47) TDP1ALDH1A1MEN1KMT2ACES1
SCHEMBL19230395 0.81 CES1 (0.43) ALDH1A1LMNAHIF1ACES1TTR
SCHEMBL20414449 0.71 CES1 (0.47) HPRT1CYP1A2CYP2C9CYP2C19TDP1
SCHEMBL8603564 0.69 ALDH1A1 (0.57) ALDH1A1CES1
SCHEMBL12775946 0.68 MAPT (0.47) HPRT1CYP1A2TDP1ALDH1A1MEN1
SCHEMBL9180379 0.68 ALDH1A1 (0.51) TDP1ALDH1A1MEN1KMT2AUSP2
SCHEMBL6152233 0.68 HPRT1 (0.45) HPRT1CYP1A2CYP2C9CYP2C19TDP1
SCHEMBL2604372 0.68 MAPT (0.41) TDP1ALDH1A1MEN1KMT2ALMNA
SCHEMBL25510 0.67 HPRT1 (1.00) HPRT1CYP1A2CYP2C9CYP2C19TDP1
Chrysene SCHEMBL384031 0.67 HPRT1 (1.00) HPRT1CYP1A2CYP2C9CYP2C19TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017137142-A1 A POLYMER, COMPOSITION, FORMING SACRIFICIAL LAYER AND METHOD FOR SEMICONDUCTOR DEVICE THEREWITH AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) 2017-08-17 WO disclosed