Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230397 | 0.92 | HPRT1 (0.45) | CES1TTRDNMT1MAPTMEN1 | |
| SCHEMBL19230395 | 0.85 | CES1 (0.43) | CES1TTRCASP3ALDH1A1PKM | |
| SCHEMBL20414449 | 0.79 | CES1 (0.47) | CES1DNMT1MAPTMEN1KMT2A | |
| SCHEMBL12775946 | 0.76 | MAPT (0.47) | DNMT1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8603564 | 0.76 | ALDH1A1 (0.57) | CES1ALDH1A1 | |
| SCHEMBL2604372 | 0.75 | MAPT (0.41) | CES1DNMT1MAPTMEN1KMT2A | |
| SCHEMBL4109839 | 0.73 | DNMT1 (0.50) | DNMT1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9180379 | 0.71 | ALDH1A1 (0.51) | CES1TTRDNMT1MAPTMEN1 | |
| SCHEMBL12776299 | 0.70 | DNMT1 (0.43) | CES1TTRDNMT1MAPTMEN1 | |
| SCHEMBL2578936 | 0.69 | ALDH1A1 (0.48) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017137142-A1 | A POLYMER, COMPOSITION, FORMING SACRIFICIAL LAYER AND METHOD FOR SEMICONDUCTOR DEVICE THEREWITH | AZ Electronic Materials (Luxembourg) S.à.r.l. (LU) | 2017-08-17 | — | — | WO | disclosed |