Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.32 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230560 | 0.87 | NR1H4 (0.37) | MRGPRX4NR1H4ITGB3ITGA2BSLC8A1 | |
| SCHEMBL19230827 | 0.86 | NR1H4 (0.37) | NR1H4ITGB3ITGA2BSLC8A1 | |
| SCHEMBL19230696 | 0.85 | ITGB3 (0.39) | NR1H4ITGB3ITGA2BSLC8A1 | |
| SCHEMBL19230547 | 0.84 | PPARD (0.34) | SLC8A1 | |
| SCHEMBL19230634 | 0.83 | NR1H4 (0.37) | NR1H4SLC8A1 | |
| SCHEMBL19230657 | 0.82 | SLC8A1 (0.36) | ITGB3ITGA2BSLC8A1 | |
| SCHEMBL19230377 | 0.82 | SLC8A1 (0.37) | NR1H4ITGB3ITGA2BSLC8A1 | |
| SCHEMBL19230544 | 0.81 | ITGB3 (0.35) | NR1H4ITGB3ITGA2BSLC8A1 | |
| SCHEMBL19230784 | 0.81 | SLC8A1 (0.36) | ITGB3ITGA2BSLC8A1 | |
| SCHEMBL19230654 | 0.80 | ITGB3 (0.33) | ITGB3ITGA2BSLC8A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |