Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | SLC8A1 | P32418 | 10/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.30 |
| ▸ | CCR3 | P51677 | 2/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19230654 | 0.86 | ITGB3 (0.33) | SLC8A1 | |
| SCHEMBL19230696 | 0.85 | ITGB3 (0.39) | SLC8A1 | |
| SCHEMBL19230633 | 0.84 | MRGPRX4 (0.38) | SLC8A1 | |
| SCHEMBL19230544 | 0.84 | ITGB3 (0.35) | SLC8A1 | |
| SCHEMBL19230520 | 0.82 | PPARG (0.33) | PPARDPPARA | |
| SCHEMBL19230569 | 0.79 | SLC8A1 (0.34) | SLC8A1 | |
| SCHEMBL19230598 | 0.79 | FAAH (0.34) | PPARDPPARASLC8A1 | |
| SCHEMBL19230606 | 0.79 | ESR1 (0.38) | SLC8A1 | |
| SCHEMBL19230970 | 0.79 | NR1H4 (0.31) | — | |
| SCHEMBL19230560 | 0.79 | NR1H4 (0.37) | PPARDPPARASLC8A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |