Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 16/20 | 0.34 |
| ▸ | FXR2 | P51116 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879009 | 0.82 | NR1H4 (0.48) | NR1H4FXR2 | |
| SCHEMBL12879066 | 0.79 | NR1H4 (0.51) | NR1H4FXR2 | |
| SCHEMBL12879061 | 0.76 | NR1H4 (0.49) | NR1H4FXR2 | |
| SCHEMBL19620248 | 0.75 | NR1H4 (0.51) | NR1H4 | |
| SCHEMBL19230581 | 0.75 | NR1H4 (0.58) | NR1H4FXR2 | |
| SCHEMBL12879262 | 0.75 | NR1H4 (0.41) | NR1H4MEN1KMT2A | |
| SCHEMBL23474093 | 0.75 | ACACB (0.38) | NR1H4 | |
| SCHEMBL12879010 | 0.75 | NR1H4 (0.57) | NR1H4FXR2 | |
| SCHEMBL19230579 | 0.73 | NR1H4 (0.54) | NR1H4FXR2 | |
| SCHEMBL12879085 | 0.72 | NR1H4 (0.58) | NR1H4FXR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133521-A1 | FXR RECEPTOR AGONIST | 山东轩竹医药科技有限公司 | 2017-08-10 | — | — | WO | disclosed |