Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.55 |
| ▸ | ARG2 | P78540 | 4/20 | 0.50 |
| ▸ | ARG1 | P05089 | 3/20 | 0.50 |
| ▸ | NOS2 | P35228 | 6/20 | 0.49 |
| ▸ | NOS1 | P29475 | 4/20 | 0.49 |
| ▸ | NOS3 | P29474 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21861898 | 0.96 | GSR (0.54) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL17431026 | 0.86 | GSR (0.57) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL15222427 | 0.86 | GSR (0.57) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL19232136 | 0.85 | KIF11 (0.48) | GSRNOS2NOS1NOS3CYP1A2 | |
| SCHEMBL5828956 | 0.83 | GSR (0.54) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL3472931 | 0.83 | GSR (0.54) | GSRARG2ARG1NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL15372840 | 0.82 | GSR (0.52) | GSRARG2ARG1NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL7130280 | 0.82 | GSR (0.52) | GSRARG2ARG1NOS2NOS1 | |
| Hydrochloric Acid SCHEMBL15372842 | 0.82 | GSR (0.52) | GSRARG2ARG1NOS2NOS1 | |
| SCHEMBL10052913 | 0.81 | GSR (0.56) | GSRARG2ARG1NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136581-A1 | ANTI-EGFR ANTIBODY DRUG CONJUGATE | MEDITOPE BIOSCIENCES, INC. (US) | 2017-08-10 | — | — | WO | disclosed |