Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.48 |
| ▸ | GSR | P00390 | 2/20 | 0.48 |
| ▸ | GRM8 | O00222 | 1/20 | 0.48 |
| ▸ | GRM6 | O15303 | 1/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.48 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.48 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.48 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21861898 | 0.89 | GSR (0.54) | GSRGRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL19232133 | 0.85 | GSR (0.55) | GSRCYP1A2GRIK1SLC1A2SLC1A1 | |
| SCHEMBL14420362 | 0.84 | KIF11 (0.50) | KIF11GSRGRM8GRM6GRIN2D | |
| SCHEMBL5697661 | 0.84 | KIF11 (0.50) | KIF11GSRGRM8GRM6GRIN2D | |
| SCHEMBL8418914 | 0.84 | KIF11 (0.50) | KIF11GSRGRM8GRM6GRIN2D | |
| SCHEMBL25661140 | 0.82 | NOS2 (0.51) | KIF11GSRGRM8GRM6GRIN2D | |
| SCHEMBL25661068 | 0.82 | NOS2 (0.51) | KIF11GSRGRM8GRM6GRIN2D | |
| Hydrochloric Acid SCHEMBL29213474 | 0.82 | NOS2 (0.50) | KIF11GSRGRM8GRM6GRIN2D | |
| SCHEMBL25660541 | 0.82 | NOS2 (0.51) | KIF11GSRGRM8GRM6GRIN2D | |
| Hydrochloric Acid SCHEMBL319257 | 0.82 | NOS2 (0.50) | KIF11GSRGRM8GRM6GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136581-A1 | ANTI-EGFR ANTIBODY DRUG CONJUGATE | MEDITOPE BIOSCIENCES, INC. (US) | 2017-08-10 | — | — | WO | disclosed |