Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.50 |
| ▸ | CFD | P00746 | 14/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19234388 | 0.88 | P2RX7 (0.47) | P2RX7CFD | |
| SCHEMBL12480319 | 0.87 | P2RX7 (0.51) | P2RX7CFDFPR3FPR2 | |
| SCHEMBL30052463 | 0.87 | P2RX7 (0.51) | P2RX7CFDFPR3FPR2 | |
| SCHEMBL30051988 | 0.87 | P2RX7 (0.51) | P2RX7CFDFPR3FPR2 | |
| SCHEMBL18309345 | 0.87 | P2RX7 (0.51) | P2RX7CFDFPR3FPR2 | |
| SCHEMBL29095042 | 0.87 | P2RX7 (0.51) | P2RX7CFDFPR3FPR2 | |
| SCHEMBL19234120 | 0.86 | P2RX7 (0.53) | P2RX7CFDFPR3FPR2 | |
| Hydrochloric Acid SCHEMBL17023366 | 0.86 | P2RX7 (0.50) | P2RX7CFDFPR3FPR2 | |
| SCHEMBL19234461 | 0.86 | P2RX7 (0.53) | P2RX7CFDFPR3FPR2 | |
| Hydrochloric Acid SCHEMBL17046838 | 0.86 | P2RX7 (0.50) | P2RX7CFDFPR3FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661433-B1 | INDOLE COMPOUNDS OR ANALOGUES THEREOF USEFUL FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION (AMD) | NOVARTIS AG (CH) | 2017-08-16 | — | — | EP | disclosed |