Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1923464 | 1.00 | TP53 (0.42) | TP53SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL16977317 | 0.84 | SLC7A5 (0.40) | TP53SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL31506280 | 0.82 | SLC22A6 (0.37) | GABRR1CYP1A2LMNAMMP1MMP2 | |
| SCHEMBL2441109 | 0.79 | — | — | |
| SCHEMBL3939728 | 0.79 | — | — | |
| SCHEMBL2441111 | 0.79 | — | — | |
| SCHEMBL468406 | 0.77 | TP53 (0.38) | TP53SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL468405 | 0.77 | TP53 (0.38) | TP53SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL14376677 | 0.77 | — | — | |
| SCHEMBL28011344 | 0.77 | TP53 (0.38) | TP53SLC7A5SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309105-B2 | Triflusal-containing polymers for stent coating | PALAU PHARMA, S.A. (ES) | 2012-11-13 | — | — | US | disclosed |
| EP-1940894-B1 | TRIFLUSAL-CONTAINING POLYMERS FOR STENT COATING | PALAU PHARMA SA (ES) | 2011-06-08 | — | — | EP | disclosed |
| US-7445789-B2 | Biocompatible polymeric systems carrying triflusal or HTB | PALAU PHARMA, S.A. (ES) | 2008-11-04 | — | — | US | disclosed |
| US-20080249617-A1 | Triflusal-Containing Polymers for Stent Coating | PALAU PHARMA, S.A. (ES) | 2008-10-09 | — | — | US | disclosed |
| EP-1940894-A1 | TRIFLUSAL-CONTAINING POLYMERS FOR STENT COATING | Palau Pharma, S.A. (ES) | 2008-07-09 | — | — | EP | disclosed |
| EP-1767552-A1 | Triflusal-containing polymers for stent coating | Palau Pharma, S.A. (ES) | 2007-03-28 | — | — | EP | disclosed |
| WO-2007014787-A1 | TRIFLUSAL-CONTAINING POLYMERS FOR STENT COATING | PALAU PHARMA, S.A. (ES) | 2007-02-08 | — | — | WO | disclosed |
| US-20060067955-A1 | Biocompatible polymeric systems carrying triflusal or HTB | J. URIACH & CIA S.A. (ES) | 2006-03-30 | — | — | US | disclosed |
| US-6979465-B1 | Biocompatible polymer systems carrying triflusal or HTB | J. URIACH & CIA, S.A. (ES) | 2005-12-27 | — | — | US | disclosed |
| EP-1210954-B1 | NEW BIOCOMPATIBLE POLYMER SYSTEMS CARRYING TRIFLUSAL OR HTB | URIACH Y COMPANIA S A J (ES) | 2005-04-27 | — | — | EP | disclosed |
| EP-1210954-A1 | NEW BIOCOMPATIBLE POLYMER SYSTEMS CARRYING TRIFLUSAL OR HTB | J. URIACH & CIA. S.A. (ES) | 2002-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060067955-A1 | Biocompatible polymeric systems carrying triflusal or HTB | HTR2B, HMBS, TLL1 | TP53 1195/4885SLC7A5 1749/4885SLC1A3 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.