Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4844468 | 0.81 | EPHX2 (0.56) | EPHX2CD274HPGDLMNAALDH1A1 | |
| SCHEMBL19234948 | 0.79 | LMNA (0.47) | EPHX2CD274HPGDLMNAABHD6 | |
| SCHEMBL3222256 | 0.77 | EPHX2 (0.54) | EPHX2CD274HPGDLMNAALDH1A1 | |
| SCHEMBL5741437 | 0.75 | MAPK1 (0.59) | EPHX2CD274HPGDLMNAALDH1A1 | |
| SCHEMBL19234914 | 0.75 | LMNA (0.48) | EPHX2LMNAABHD6SMN1; SMN2CNR1 | |
| SCHEMBL19234910 | 0.75 | LMNA (0.48) | EPHX2LMNAABHD6SMN1; SMN2CNR1 | |
| SCHEMBL27516592 | 0.75 | HRH3 (0.58) | EPHX2CD274LMNAALDH1A1HTR1A | |
| SCHEMBL19234903 | 0.75 | LMNA (0.48) | EPHX2LMNAABHD6SMN1; SMN2CNR1 | |
| SCHEMBL5549334 | 0.72 | MEN1 (0.68) | EPHX2LMNAKCNH2CNR1POLB | |
| SCHEMBL18731590 | 0.71 | EPHX2 (0.51) | EPHX2CD274HPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136943-A1 | SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME | CDRD VENTURES INC. (CA) | 2017-08-17 | — | — | WO | disclosed |