Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27539586 | 0.87 | ACP1 (0.51) | HRH3CYP1A2RAB9A | |
| SCHEMBL5881631 | 0.82 | HRH3 (0.50) | HRH3CYP3A4ALDH1A1USP2CYP1A2 | |
| SCHEMBL4844468 | 0.81 | EPHX2 (0.56) | EPHX2LMNAALDH1A1CD274HTR1A | |
| SCHEMBL5741437 | 0.81 | MAPK1 (0.59) | EPHX2LMNAALDH1A1HSD17B10CD274 | |
| SCHEMBL3222256 | 0.80 | EPHX2 (0.54) | EPHX2LMNAALDH1A1CD274POLB | |
| SCHEMBL5881840 | 0.78 | KDM4E (0.64) | LMNAALDH1A1POLBRAB9A | |
| SCHEMBL6103930 | 0.78 | HRH3 (0.83) | HRH3LMNAALDH1A1USP2CYP1A2 | |
| SCHEMBL13547569 | 0.76 | TRPC5 (0.49) | CYP3A4LMNAALDH1A1POLB | |
| SCHEMBL13841388 | 0.75 | TSHR (0.60) | CYP3A4LMNAUSP2CYP1A2HSD17B10 | |
| SCHEMBL19234947 | 0.75 | EPHX2 (0.47) | EPHX2LMNAALDH1A1CD274POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1250531-C | Novel compounds | ASTRAZENECA AB (SE) | 2006-04-12 | — | — | CN | disclosed |
| CN-1503787-A | Novel compounds | — | 2004-06-09 | — | — | CN | disclosed |